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David Givol Selected Research

Therapeutics

2/2012HIPK2 downregulates vimentin and inhibits breast cancer cell invasion.
12/2011Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation.
12/2010Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo.
4/2010HIPK2-a therapeutical target to be (re)activated for tumor suppression: role in p53 activation and HIF-1α inhibition.

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David Givol Research Topics

Disease

18Neoplasms (Cancer)
01/2014 - 05/2003
5Hypoxia (Hypoxemia)
02/2012 - 08/2009
4Glioblastoma (Glioblastoma Multiforme)
05/2011 - 07/2007
3Breast Neoplasms (Breast Cancer)
02/2012 - 01/2009
2Carcinoma (Carcinomatosis)
05/2013 - 02/2012
2Colonic Neoplasms (Colon Cancer)
05/2013 - 12/2011
2Neoplasm Metastasis (Metastasis)
04/2013 - 04/2010
1Adenocarcinoma
01/2014
1Polyps
05/2013
1Prostatic Neoplasms (Prostate Cancer)
12/2010
1Renal Cell Carcinoma (Grawitz Tumor)
12/2010
1Lung Neoplasms (Lung Cancer)
08/2009
1Hepatocellular Carcinoma (Hepatoma)
07/2007
1Infections
07/2007
1Inflammation (Inflammations)
07/2007
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
04/2006
1Teratocarcinoma
02/2005
1Alopecia (Baldness)
02/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2003

Drug/Important Bio-Agent (IBA)

9ZincIBA
08/2012 - 05/2008
5Pharmaceutical PreparationsIBA
12/2011 - 07/2007
4Proteins (Proteins, Gene)FDA Link
12/2010 - 01/2009
2AntibodiesIBA
01/2014 - 05/2013
2Phosphotransferases (Kinase)IBA
01/2014 - 05/2010
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2012 - 05/2008
2Serine (L-Serine)FDA Link
08/2012 - 08/2009
2Oxygen (Dioxygen)IBA
12/2011 - 08/2009
2CobaltIBA
12/2011 - 08/2009
2Transcription Factors (Transcription Factor)IBA
12/2011 - 04/2006
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2010 - 08/2009
2Co-Repressor ProteinsIBA
05/2010 - 08/2009
2Small Interfering RNA (siRNA)IBA
10/2009 - 08/2009
1ParaffinIBA
05/2013
1Insulin (Novolin)FDA Link
04/2013
1Biomarkers (Surrogate Marker)IBA
08/2012
1VimentinIBA
02/2012
1Hypoxia-Inducible Factor 1IBA
12/2011
1IonsIBA
12/2011
1superoxide-forming enzymeIBA
05/2010
1Glucose (Dextrose)FDA LinkGeneric
04/2010
1Angiogenesis InhibitorsIBA
04/2010
1Protein Kinases (Protein Kinase)IBA
08/2009
1DNA (Deoxyribonucleic Acid)IBA
01/2009
1MicroRNAs (MicroRNA)IBA
11/2008
1Imatinib Mesylate (Gleevec)FDA Link
11/2008
1IronIBA
07/2007
1HepcidinsIBA
07/2007
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2005
1Left-Right Determination FactorsIBA
02/2005
1Immunologic Factors (Immunomodulators)IBA
02/2004
1ammonium trichloro(dioxoethylene-O,O'-)tellurate (AS 101)IBA
02/2004
1CalciumIBA
05/2003
1CytokinesIBA
05/2003
1Biological ProductsIBA
05/2003

Therapy/Procedure

8Drug Therapy (Chemotherapy)
01/2014 - 05/2003
4Therapeutics
02/2012 - 04/2010
2Radiotherapy
01/2014 - 05/2011